A sticking valve

Sticking with Carrots and Sticks (Sticking Points Aside): A Response to Ventakapuram, Goldberg, and Forrow

Sticking together a signal

In This Issue In This Issue Let's make liver etoxification is what livers do best, and regenerating after toxic insults is what livers do second best. All that proliferative capacity suggests that liver stem cells might be a very different and more prevalent beast than stem cells from other organs. But, on page 173, Suzuki et al. report that the fetal mouse liver, just like the adult bone marro...

Sticking Points

Nowadays a blood test usually requires a doctor’s visit, a needle poke in the arm, and a day-long wait for results to come back from a lab. So when Silicon Valley start-up Theranos promised a device that could perform more than a hundred of the most commonly ordered blood tests from just a fingerstick, doctors, patients, and investors were quick to get behind the company. Valued at $9 billion i...

Sticking together.

R signals at the neuromuscular junction and at synapses between neurons are carried by small molecules, called neurotransmitters, that are released from the presynaptic terminal and bind to ligand-gated ion channels in the postsynaptic membrane. When transmitter binds, a small pore opens through which ions flow, resulting in a transient depolarization or hyperpolarization of the membrane and tr...

Sticking with carrots and sticks (sticking points aside): a response to ventakapuram, goldberg, and forrow.

I would like to thank Sridhar Ventakapuram, Daniel Goldberg, and Lachlan Forrow for thoughtful responses to my article (1–4). All endorse my main point, that conditioning the very aid that patients need in order to become healthier on their success in becoming healthier is (usually) wrong. They may think me, however, too friendly to an approach that gives patients “carrots” or “sticks” dependin...